
Revolutionising immunotherapy and anti-infectives for the most vulnerable patients
Alphamer® technology
Driven by science
Our Alphamer® technology offers a unique approach to immunotherapy. By harnessing naturally-occurring and ubiquitous anti-glycan antibodies to engage the host immune system and redirect it towards disease targets, Alphamers enable us to combat infection in even the most vulnerable patients.


Addressing urgent unmet needs
Antibiotics underpin modern medicine. However, rising antimicrobial resistance and a growing population of high-risk patients with comorbidities and immune suppression mean that traditional approaches to anti-infectives alone are no longer sufficient.
Harnessing the host response
At Centauri, we believe that successful treatment of infection requires addressing both the pathogen and the host. Our Alphamer® technology is designed to overcome existing failures in treatment by combining direct antibacterial activity with a targeted and clinically-validated immune mechanism.
Alphamers® are powerful and versatile immunotherapeutics with the potential to transform treatment options for high-risk patients across life-threatening indications. Initially focused on infectious disease, our pipeline includes our lead clinical candidate CTX-187 – a novel immunotherapy for the treatment of Gram-negative bacterial infections.



