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Revolutionising immunotherapy and anti-infectives for the most vulnerable patients

Driven by science

Our Alphamer® technology offers a unique approach to immunotherapy. By harnessing naturally-occurring and ubiquitous anti-glycan antibodies to engage the host immune system and redirect it towards disease targets, Alphamers enable us to combat infection in even the most vulnerable patients.

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Addressing urgent unmet needs

Antibiotics underpin modern medicine. However, rising antimicrobial resistance and a growing population of high-risk patients with comorbidities and immune suppression mean that traditional approaches to anti-infectives alone are no longer sufficient.

Harnessing the host response

At Centauri, we believe that successful treatment of infection requires addressing both the pathogen and the host. Our Alphamer® technology is designed to overcome existing failures in treatment by combining direct antibacterial activity with a targeted and clinically-validated immune mechanism.

Alphamers® are powerful and versatile immunotherapeutics with the potential to transform treatment options for high-risk patients across life-threatening indications. Initially focused on infectious disease, our pipeline includes our lead clinical candidate CTX-187 – a novel immunotherapy for the treatment of Gram-negative bacterial infections.

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